

🐾 Elevate your dog’s liver health — because every wag counts!
Denamarin Liver Health Supplement by Nutramax is a veterinarian-recommended formula designed specifically for large dogs (35+ lbs) to support liver function. Featuring clinically proven ingredients SAMe and highly absorbable Silybin, it enhances antioxidant levels and promotes detoxification. Trusted for over 30 years, this supplement helps improve liver enzyme levels and overall vitality, making it a must-have for aging or liver-compromised dogs.



















| ASIN | B0011XHGR0 |
| ASIN | B0011XHGR0 |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #3,625 in Pet Supplies ( See Top 100 in Pet Supplies ) #103 in Dog Supplements & Vitamins |
| Brand Name | Nutramax Laboratories |
| Breed Recommendation | large dogs, 35 lbs and over |
| Color | blue |
| Country of Origin | United States |
| Customer Reviews | 4.7 4.7 out of 5 stars (3,587) |
| Date First Available | January 25, 2008 |
| Date First Available | January 25, 2008 |
| Directions | For dogs up to 12 lbs, 1 tablet per day. For cats up to 12 lbs, 1 tablet per day; for cats over 12 lbs one tablet twice daily. Tablets should be given on an empty stomach for optimal absorption. They may be given at least two hours after a meal or one hour before a meal. |
| Is Discontinued By Manufacturer | No |
| Item Dimensions LxWxH | 5.5 x 3.6 x 1.4 inches |
| Item Package Dimensions L x W x H | 5.63 x 3.54 x 1.46 inches |
| Item Weight | 1.6 Ounces |
| Item model number | DENAMARIN425 |
| Item model number | DENAMARIN425 |
| Manufacturer | Nutramax Laboratories Veterinary Sciences, Inc. |
| Manufacturer | Nutramax Laboratories Veterinary Sciences, Inc. |
| Model Name | Denamarin Liver Health Supplement |
| Number of Items | 1 |
| Product Dimensions | 5.5 x 3.6 x 1.4 inches; 1.6 ounces |
| Size | 30Count(Pack of 1) |
| Specific Uses for Product | Liver Health |
| Target Audience Keyword | Dogs |
H**R
Excellent Treatment for Older Fur-Kids With Liver Issues.
I foster dogs, but have chosen to specialize in the older and sicker rescued dogs. I have had many, many dogs with liver problems. But for a long time we were losing our precious furry friends, it was awful, there just was not really a very good treatment out there for an old dog with bad liver readings. The problem was that the old dogs all had arthritis, many had been brutalized and abandoned by previous owners, and there were some things that could not be fixed. However, finally we had access to a wide canine assortment of NSAID's. This was wonderful, the previous only hope was aspirin, with many associated bleeding risks, or dangerous steroids for their poor inflamed, badly healed, and otherwise painful limbs. They were always so good, even though I knew that they were suffering. Then, we suddenly had access to the wonderful mom-steroidal pain relievers. This was magic stuff. Dogs that could barely walk were bouncing around, dogs that could not climb stairs were bounding up, two steps at a time. However, there was a dark side to all of this joy...as we soon discovered. These miracle NSAID's were pretty rough on the livers of the old dogs. So much so that I was faced with the awful choice of continuing that medication, knowing that it was destroying their liver, but it was also keeping the dogs joints pain-free. My other alternative was no good alternative - no NSAIDS, just heavier and heavier doses of narcotics for the pain......helplessly watching the failing test results of my poor old pups. I lost quite a few that way, it almost killed me. Then Denamarin, and Marin came along. I use both on my old pups and it is another miraculous thing to witness. This is a nom-prescription item that magically lowered bad liver numbers, sometimes within a three or four week period.. It is very expensive, but Amazon has the best price of all. My dogs are living now, and not teetering on the edge with failing livers. It is possible to use NSAID's in conjunction with Denemarin, and the liver numbers are far better, and the dogs are not doped-up on narcotics, but can enjoy their last days. I am amazed by the breakthroughs that I have witnessed in the veterinary world over the last ten years that I have been fostering. Sometimes it is pretty magical, old dogs frolicking around my ankles each morning, demanding a treat, just like a bunch of pups. I am not a vet., I wish to make that crystal clea. I have no connection whatsoever with this company, indeed had never heard of them before my vet mentioned this drug. All that I can say is that I have had dogs my entire life, and I have witnessed far too many agonizing decisions that have had to be made. Watching an agonized old dog, painfully hobble around, or give the drug that will help with the arthritis...and have very negative effects with their livers. In the.end, we usually just tried to keep them out of pain, but they had.no good quality of life. Again, to be perfectly clear, with MY old dogs, under MY care, eating the very best of dog kibble, no fatty treats, no people food, and someone around at all times to give the drugs at the appropriate times, I have seen rapidly discernible improvement in my older guys. Not every dog reacts the same way, doses can be tricky, and.require a lot of blood testing' and fiddling with dosages, my dogs have definitely improved. Not all have a glorious outcome. But If they are willing to get out of their beds, and follow me to the kitchen to beg for food, my heart is happy. When you are working with old, injured, and sick dogs...little things matter a lot. Denemarin, along with another supplement : Marin, have made the lives of some of the older fur kids better, and happier. This will not save your old dog, there will be heart problems, cancers, and other issues upon which Denemarin has no effect. But for the dogs in the specific conditions that I have outlined, I have seen a definite difference in both the quality of life for the dog, as well as better liver readings on their blood tests. Again, it is expensive, this makes for a very hard decision for every pet lover. But, it is effective on many dogs. And that is a miracle for me. We are saving dogs that we would have lost ten years ago, and this supplement has had a lot to do with that. It is up to the pet owner, but under the conditions that I have stipulated, this is a worthwhile addition to the supplemental diet of old dogs.
G**N
Quality supplement for better digestion and quality of life for my dog.
My dog has been having liver issues and has been showing high levels of enzymes on his tests. He's about 8 years old right now and I want to make sure he's getting good care. The doc recommended a couple of types of supplements to help with those high liver enzymes and I chose the Denamarin based on reviews. So, far everything seems to be going well. My dog seems to be able to tolerate it well. He has a sensitive stomach and often throws medicine back up. He hasn't done that yet with the Denamarin. Even more positive is that his first test has come back showing decreased levels of those enzymes, so I guess it's working and doing what it's supposed to do. The price seems to be a little spendy to me for a non-prescription supplement, but it's the best one I can find and it seems to be working. What are you going to do? My dog's worth it, so he's going to get it.
W**.
A Lifesaver for My Big Furry Friend
I'm a long-time fan of this product. It contains SAMe and is safe for my large dog, which is great. It's suitable for bigger breeds, supports liver health, and boosts the immune system. It comes in a 30-count pack and uses high-quality ingredients. It's recommended by veterinarians and is definitely worth the cost. Nutramax Laboratories maintains its quality standard.
H**.
Saved My Dog's Life
I can't say enough great things about Denamarin. In August 2014, I had a feeling I should have the vet run blood work on my 11 year old lab mix. She was acting fine, and had no real health issues, it was just a nagging feeling. We ran the blood panel, and it was a good thing we did. ALT is a liver enzyme that is released when there is damage occurring to the liver. A normal ALT value is ideally below 110, my dog's was 390. Not good, that meant there was some serious liver damage happening. We ran a lot of tests to see what the cause could be. Ultrasound showed nothing abnormal. We did a few rounds of antibiotics in case it was some sort of hepatitis. Nothing really made a difference, and we couldn't see what the issue was. So we started her on Denamarin. I really didn't think it would do too much, but I was willing to try. Slowly her ALT values began to lower, I'll post a little table at the bottom so you can see. By October her ALT was down to 147! Then in November we ran out of Denamarin for a couple weeks. Honestly, I wasn't too concerned. I assumed she was just getting over whatever had been the issue, I didn't think the key to her improving was the Denamarin. The next time we measured her ALT in December it was back up to 243. We never ran out of Denamarin again after that, and as of May 2015 her ALT value was 46! Thats right, from a high of 390, down to 46. I could not be happier. Given her age, I did not think that we would be back in the normal range for much. But not only is her ALT back to normal, but so is every blood value they tested. This has been worth every penny. Helpful tip: it is probably a lot cheaper on Amazon than thru the vet. I save $20 a box here. --ALT Values on Denamarin-- Aug 2014 390 Sept 2014 290 Oct 2014 147 Dec 2014 243 (this is when we ran out of Denamarin) Jan 2015 114 May 2015 46
R**K
Keeping my dog alive
These have been cleaning my dog's liver for over 3 years. Save yourself some money and go get them at Costco for $55 a box.
D**0
Meet our expectations
Just what we needed. Average price. Average delivery. Meet all our expectations
M**N
they work for our dog
Our vet recommended these and I love how fast they get shipped! They seem to be helping her liver as her numbers are in a normal range now.
B**S
Great supplement for my pet
When I was told my dog needed this supplement the first place I checked was Amazon. With fail they did carry it. Received it the next day and she has been on it since. I would recommend to all pet owners with this problem.
A**R
This made such a difference in our dog that has liver enzyme issues. Not sure how it is possible, but she went 4 months Wii’s seizure while taking this. Before it was 2-3 weeks. She had more energy and basically was a different dog.
N**Y
Arrived in a timely manner. My lab/doberman had copper storage disease, diagnosed at 3 years old. The vet gave her 2 weeks. Along with Zinc, homemade food, and distilled water, it seemed to have helped, and I was able to give her 3 more months.
P**E
Good price. Fast delivery
Trustpilot
3 weeks ago
1 month ago