Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg

I have a 4-year-old Maine Coon with a sensory processing disorder. My big boy, Barnum, has trouble processing textures and noises. I have the only Maine Coon in America who HATES to be brushed no matter the brush or comb used. (We have 12.) Everyday noises — the doorbell, microwave alarm, TV volume — completely unhinge him and send him running for his life. Prozac helped to some degree, but it also flattened him emotionally and didn’t fully address the sensory overload. Since adding Zylkene alongside an reduced Prozac dose, the change has been remarkable. Barnum is calmer (no longer flinching when the duct work in the attic pops or the ice maker drops ice), more social, and genuinely enjoying life again. He seeks affection, engages in play, and even participates in brush sessions willingly (with freeze dried chicken incentives!). The difference is subtle but profound — his nervous system feels soothed, not sedated. I give him 1 capsule every morning. 2 made him sleep all day. Zylkene has balanced his sensory overload and allowed his personality and spirit to come back. He’s alert but regulated, playful but not anxious, and much more comfortable navigating the household and daily life. Any owner of a cat with anxiety or sensory issue should try Zylkene. Worth every penny!

We love these, they help calm our dog. Max has breathing difficulties and these help him relax and breath better

My experience comes from a cat shelter and, in recent years, working as a professional cat behavior consultant. It's hard to know with supplements if they really are effective, especially when they are used in conjunction with other behavior modification strategies. I can say that I used them with my cats for about a month as we were transitioning into our new home, and I thought they were helpful. I like that they have fewer potential side effects than prescription medication. Most cats don't mind the taste. For cats with more discerning taste, you can give the gel caps whole, on a lick mat in a pile of mixed-texture treats. The only drawback, from my perspective, is these supplements are pricey, which makes them less feasible for long-term use.

Absolutely amazing anxiety/ panic meds. These made a difference in my dog's anxiety and panic. They work much better than I could every hope for and he has C-PTSD and I cried and tried every to help him, and nothing did until I discovered these.

It works but I wanted something where my cat could just enjoy chilling out with family, I know cats sleep a lot anyway but this really knocks him out where I don’t get enough time with him. I hope that eventually he will relax in his new home and I can enjoy quality time with him.

My cat is a super sleuth. She sniffed out the solliquin and simply wouldn't take it again. This, she can't sniff out. She eats her wet food like normal. It's helping her be very patient with the new kitten.

Our cat was sometimes urinating in the house in places other than the litter box. The veterinarian suggested that we try this and it has worked very well. The capsules are easy to pull apart so that the powder can be mixed into cat food.

I've been pretty happy with Zylkene! I ordered it for two of my anxious senior dogs. It did not work for one of them, but his issues seem to run deeper and he's required something a bit stronger from the vet. For my chihuahua, though, she would tumble every time we ran the dryer before we started her on Zylkene. Since it's a capsule, I just open it and sprinkle it on her food each morning, and it takes the edge off enough that she no longer has issues when we run the dryer.