Will oral io replacement brushes work in an oral genesis 6000?

The package does not indicate anything about the genesis 6000.

Coming from a Sonicare user, what’s the point of the hole in the toothbrush head on all oral b brushes? No answers from Google came up.

The holes in the back of the toothbrush head on Oral B is so you can rinse and clean out any leftover toothpaste on the bristles

Is this product compatible with Oral B iO series 7s?

Yes, all “iO” models utilize the same replacement brush heads.

Can this oral-b io be used on all oral-b ?

The IO is a different system. You must have the special IO brushes for it and these brushes do t fit the other models

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