---
product_id: 543984741
title: "Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml)"
brand: "isdin"
price: "10574963₫"
currency: VND
in_stock: true
reviews_count: 8
category: "Isdin"
url: https://www.desertcart.vn/products/543984741-isdinceutics-retinal-advanced-rejuvenating-facial-night-serum-with-retinaldehyde-melatonin
store_origin: VN
region: Vietnam
---

# 43% wrinkle reduction in 4 weeks Night serum with melatonin for skin rejuvenation Dual-phase formula for maximum ingredient stability Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml)

**Brand:** isdin
**Price:** 10574963₫
**Availability:** ✅ In Stock

## Summary

> 🌟 Wake up to younger, glowing skin every morning!

## Quick Answers

- **What is this?** Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml) by isdin
- **How much does it cost?** 10574963₫ with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vn](https://www.desertcart.vn/products/543984741-isdinceutics-retinal-advanced-rejuvenating-facial-night-serum-with-retinaldehyde-melatonin)

## Best For

- isdin enthusiasts

## Why This Product

- Trusted isdin brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Nighttime Skin Rejuvenation:** Melatonin-infused serum works overnight to restore radiance and elasticity while you sleep.
- • **Universal Skin Compatibility:** Tested and trusted for all skin types, including sensitive skin, so you never have to compromise.
- • **Clinically Proven Youth Boost:** Clinically shown to reduce wrinkles by 43% in just 4 weeks, visibly turning back the clock.
- • **Advanced Dual-Phase Technology:** Innovative two-phase formula locks in potency, ensuring retinaldehyde and melatonin stay fresh and effective.
- • **Gentle Yet Powerful Retinaldehyde:** A potent retinoid that smooths texture and firms skin without harsh irritation—even on sensitive skin.

## Overview

ISDIN Isdinceutics Retinal Advanced is a 50ml rejuvenating night serum formulated with retinaldehyde and melatonin. Clinically proven to reduce wrinkles by 43% in 4 weeks, its dual-phase technology preserves ingredient potency for maximum anti-aging benefits. Suitable for all skin types, including sensitive skin, this serum smooths texture, firms skin, and boosts radiance overnight.

## Description

desertcart.com: ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml) : Beauty & Personal Care

Review: First Retinoid Product - so far so good! - I’ve never used retinal/retinol etc, so using this product is my very first attempt. I am 40+, fair skin, sensitive skin, dry skin, med/large pores, still prone to hormonal breakouts, some sun damage freckling, pretty deep 11s, and very minor wrinkles anywhere else. I started using this right around 2/1/24. It’s now 2 months of almost nightly use since (I’ve skipped a couple nights here or there just from schedule issues). I do use a full 2 pumps each time, every night, and I run the excess down my neck and upper chest to help with signs of aging there. I thought FOR SURE I would have bad peeling, redness, etc because I have sensitive skin and usually EVERYTHING makes me red or break out. But this hansy been bad at all! I started to think that might mean it’s a dud product, but I have been going thru “purge” for about 3-4 weeks. Not constant, but a couple of rounds of very agitated pimples. Moreso than I usually get, and I am used to have them every month with my cycle. So that makes me feel like it’s doing SOMETHING! I think I may be on the downward slope of the purge…. Hopefully. How does my skin feel or look? Well, it actually does feel more hydrated and softer than ever. I love that! It looks slightly more even tone (between the breakout areas when I’m having pimples and generally all over when I’m not having a breakout.) I also feel like I’m seeing a little more radiance or glow. Nothing miraculous, but just a little more shine and luster. I have not noticed a reduction in my deep 11s or my 2 very fine forehead lines. So far I’m happy. It’s such an expensive product I hate that you have to spend so much to find out if it works, but I feel like the signs I’m seeing now support continued use and expense. At 2 months, it looks to me like I might have 1 month of product left in the jar. For the price I paid, if it lasts 3 months, that’s about $62 a month ($744 a year!). I’ve never had an rx from a derm, so I’m not sure how that compares to prescription and office visit costs. I’m going to continue trying this for the full year. If I feel confident that I’m seeing results, I’ll do a cost comparison of actually getting on and maintaining a retinoid rx or just continuing this product. Will update!
Review: Top skincare product - The best product!! Have been using for 9 months and have seen a significant improvement. My skin is more glowing and have seen a decrease in dark spots. Worth the price

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B0CC9W3VWR |
| Best Sellers Rank | #53,445 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #1,120 in Facial Serums |
| Customer Reviews | 4.6 4.6 out of 5 stars (182) |
| Department  | womens |
| Manufacturer  | ISDIN |
| Package Dimensions  | 7.09 x 4.13 x 3.35 inches; 9.59 ounces |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** ISDIN
- **Item Volume:** 1.7 Fluid Ounces
- **Number of Items:** 1
- **Skin Type:** All

## Images

![Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml) - Image 1](https://m.media-amazon.com/images/I/51pcEQVydwL.jpg)

## Questions & Answers

**Q: Is Retinal Advanced suitable for sensitive skin?**
A: Yes! It’s suitable for all skin types. Retinal Advanced has been clinically tested on a wide range of skin types, including sensitive skin

**Q: Can I use it day and night?**
A: The use of retinoids can make the skin more sensitive to external factors, meaning that the effect of sun exposure can be more intense. For this reason, we recommend using it at night, followed by a broad spectrum sunscreen in the morning.

**Q: Can I use it at any time of the year?**
A: Yes, once your skin is retinized, you can use Retinal Advanced at night all year round. No matter the time of year: always apply sun protection the next morning!

## Customer Reviews

### ⭐⭐⭐⭐⭐ First Retinoid Product - so far so good!
*by R***B on April 6, 2024*

I’ve never used retinal/retinol etc, so using this product is my very first attempt. I am 40+, fair skin, sensitive skin, dry skin, med/large pores, still prone to hormonal breakouts, some sun damage freckling, pretty deep 11s, and very minor wrinkles anywhere else. I started using this right around 2/1/24. It’s now 2 months of almost nightly use since (I’ve skipped a couple nights here or there just from schedule issues). I do use a full 2 pumps each time, every night, and I run the excess down my neck and upper chest to help with signs of aging there. I thought FOR SURE I would have bad peeling, redness, etc because I have sensitive skin and usually EVERYTHING makes me red or break out. But this hansy been bad at all! I started to think that might mean it’s a dud product, but I have been going thru “purge” for about 3-4 weeks. Not constant, but a couple of rounds of very agitated pimples. Moreso than I usually get, and I am used to have them every month with my cycle. So that makes me feel like it’s doing SOMETHING! I think I may be on the downward slope of the purge…. Hopefully. How does my skin feel or look? Well, it actually does feel more hydrated and softer than ever. I love that! It looks slightly more even tone (between the breakout areas when I’m having pimples and generally all over when I’m not having a breakout.) I also feel like I’m seeing a little more radiance or glow. Nothing miraculous, but just a little more shine and luster. I have not noticed a reduction in my deep 11s or my 2 very fine forehead lines. So far I’m happy. It’s such an expensive product I hate that you have to spend so much to find out if it works, but I feel like the signs I’m seeing now support continued use and expense. At 2 months, it looks to me like I might have 1 month of product left in the jar. For the price I paid, if it lasts 3 months, that’s about $62 a month ($744 a year!). I’ve never had an rx from a derm, so I’m not sure how that compares to prescription and office visit costs. I’m going to continue trying this for the full year. If I feel confident that I’m seeing results, I’ll do a cost comparison of actually getting on and maintaining a retinoid rx or just continuing this product. Will update!

### ⭐⭐⭐⭐⭐ Top skincare product
*by A***R on December 16, 2025*

The best product!! Have been using for 9 months and have seen a significant improvement. My skin is more glowing and have seen a decrease in dark spots. Worth the price

### ⭐⭐⭐⭐⭐ Excellent retinol
*by K***T on October 13, 2025*

Looooooove what this ISDIN retinol does to my skin. I purchased it originally from a pharmacy overseas as a recommendation from the pharmacist. I wanted to have smoother skin. I purchased it again off Amazon when I ran out. Great product! Just a pea size amount at night and moisturizer afterwards.

## Frequently Bought Together

- ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml)
- ISDIN Eryfotona Actinica Zinc Oxide and 100% Mineral Sunscreen Broad Spectrum SPF 50+, No White Cast, Suitable for Sensitive Skin
- Vitamin C and Hyaluronic Acid Serum ampoule, Flavo-C Ultraglican by ISDIN

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*Product available on Desertcart Vietnam*
*Store origin: VN*
*Last updated: 2026-01-29*