Spermidine Supplement - 180 Capsules, 6mg Spermidine derived from 600mg Wheat Germ Extract with 50mg Thiamin & 50mg Zinc, 99% Pure with 3rd Party Certified, Vegan-Friendly & Non-GMO

I've been using other LongevityBox products for a while and was delighted to see that they had added spermidine to their range. Unlike other commentors here, I know that there are many supplements (like lichen derived natural vitamin D) and other foods (like orange juice and bakers yeast) where a higher concentration of the active ingredient is achieved by extracting it from the source material (in this case wheat germ) and then combining those extractions to form a higher concentration, therefore making 10mg per 1 gram easily achievable. Like other people, this Spermidine has a taste that I'm not overly keen on but I find it easily hidden by mixing it with a meal or a bit of flavoured yoghurt. The high potency of Spermidine makes this worthwhile, for me at least.

Love this brand . Good ingredients . Helps with antiaging .

This company produces good quality supplements, shame about this. The recommended dosage has very high amounts of zinc and thiamin (B1). Take this in to consideration when buying.

While not as discussed as much as resveratrol or NMN, spermidine is one of the most interesting and possibly effective supplements for longevity and health. Spermidine is a naturally occurring polyamine compound that helps a person’s body mimics fasting and is thought to aid with autophagy, which is the process of cellular rejuvenation. Spermidine plays a key role in cellular growth and proliferation, as well as cell death and autophagy (a cellular quality control process where cells breakdown all the junk our bodies no longer need). . By clearing out damaged, dysfunctional parts within cells, it can restore balance for longer-lasting vitality – enabling each of us to lead healthier lives as we continue aging gracefully. Spermidine used as a dietary supplement in mice studies has been shown to: Extends lifespan across species Promotes cardioprotection Promotes neuroprotection Induces autophagy for removal of intracellular accumulation of toxic debris Enhance mitochondrial metabolic function and respiration Exhibits anti-inflammatory and antioxidant properties Improves proteostasis These studies need to be replicated in humans to provide further evidence. You can get two types of spermidine: synthetic or food derived forms of spermidine. Food based spermidine supplements are normally made from fermented wheat germ extract. Spermidine has been in the human food chain for thousands of years and can be found in foods like: Wheat germ and some other cereals Mushrooms Broccoli Cauliflower Fresh green pepper Tempeh This supplement also comes with thiamine and zinc because studies have shown that they improve the immune response in your body and contribute to the process of metabolising food into energy – a key part of the Autophagy process. Tip: If you are intermittent fasting, I recommend taking Spermidine with your last meal of the day to enhance your body’s move into ketosis and autophagy. Spermidine is a powerful compound that has the potential to extend lifespan and improve overall health. By activating autophagy, spermidine helps to promote healthy aging and protect against age-related diseases. Whether through diet, supplements, or fasting, increasing your spermidine levels can have a profound impact on your well-being. Spermidine itself is plant-sourced from wheatgerm, and the capsules are vegan-friendly too. The capsules are easy to swallow and I noticed a difference in my sleep after just a few days of using them. I have more focus throughout the day and have a better sense of mental clarity and focus, which is definitely helpful for getting through my day. Overall, it is a good product, with promising science, and you get good service from a reliable brand. Highly recommend. Hope you found this helpful.

I’ve been taking this since August. I was concerned about the high level of zinc so have been taking a reduced dose of two or three capsules per day (instead of four). I emailed the founder regarding the zinc content and didn’t really get a clear understanding as to why it is so much higher than recommended daily amount (RDA). I take it early in the day as in the evenings I sometimes feel more awake. So recommend taking after breakfast/lunch. Interestingly, I’m seeing faster and thicker nail growth since taking this supplement. So something is definitely happening at a cellular level. My farts smell different since taking it. Something has changed and I suspect it’s having a positive impact.

I am always impressed with the simplicity and purity of Longevity Box supplements, you get what's on the pack with no unnecessary additives or vitamins that may conflict with anything else I'm taking. You get 3 packs of 120 capsules and are supposed to take 4 a day. The first time I took them I got almost instantly nauseous so I then only took 2 a day and worked my way up and haven't really had issues anymore. I have heard people mention that Spermidine has a really bad smell but they just smell like any supplements to me, not unpleasant. I read that Spermidine can help with re-growing and general health of hair which I've been struggling with for the past few months due to stress. I have been taking these capsules daily for almost a month and have been experiencing A LOT less shedding which was happening non-stop. The primary function of Spermidine being timely recycling and replacing of cells is a good reason to take it for everybody, especially from late twenties onwards as those processes slow down with age, only one pack in and I already noticed improvements in my hair so it must also be doing good for other parts of my body, will continue to take these and repurchase in the future.

I've been ordering this since early 2024 on Subscribe and Save, every 2 months, thought it was a great product reasonably priced. It was only when I ran out recently that I discovered the company surreptitiously changed the quantity from 120 to 60 for the same price. So I've cancelled my Subscribe and Save and switched to an alternative product. Even if it's a slightly lower dosage, it's way more cost effective now.

Nothing wrong with the product itself, but the advert implies 120 caps of 10mg product. In fact, to get 10 mg you have to take 4 caps so you only receive 30 doses.