- NAD+ Booster – Nicotinamide Riboside Alternative (NAD3) for Men & Women | Anti Aging NRF2 Activator, 312 mg per Serving – Natural Energy Supplement for Longevity & Cellular Health, 30 Veggie Pills

I am a 65 year old female who has had cancer twice, and have been in remission from stage 4 metastatic cancer for 11 years, due in part I believe to a regimen of supplements including resveratrol, quercetin, Vitamin C, Vitamin D3, and many others. I also walk 3 miles per day, and have tried to avoid sugar and refined carbs for much of that time. Throughout the years I have been following anti-aging and anti-cancer research, as a curious layperson. I have explored writings and videos by David Sinclair of Harvard, Leonard Guarente of MIT, and others, leading me to the recent reports on the postulated benefits to humans of NAD precursor, Nicotinimide Riboside. Leonard Guarente himself takes it, according to his Elyseum website. I started taking the recommended dose in early February, 2015, and can report some positive results, although I believe the dosage level is critical and probably varies widely, depending on one’s age and health status. My experience has been that the prescribed dose of 250 mg. is simply too much. It revved me up, but the rebound effect was very noticeable--exhaustion. A suitable analogy might be constantly gunning and red-lining one’s old, inefficient engine. So I cut back to a half dose every other day. Much better. I still feel energetic--and optimistic--but am not completely exhausted hours later after the initial burst of energy has waned. It would certainly seem logical that younger, healthy, and/or athletic folks already have sufficient amounts of NAD, so they probably wouldn't notice much if any improvement from supplementation with NR. However, old folks have NAD deficiency as a result of aging, and probably see a much greater benefit from supplementation with NR. which increases NAD. I am guessing that most of the folks reporting little or no benefit from NR are either younger & healthy and have plenty of NAD; or, perhaps are taking far more than they need, producing some sort of negative hormesis-like response; or are not taking complementary doses of resveratrol, or other pterostilbenes, which operate in tandem with NAD as a substrate to influence anti-aging sirtuins. An update: I am now 68 and still taking NR from various makers, who add various components along with NR (all Niagen based) and at various dosages.. The 250 mg. dose is now my standard, however, and I no longer have the exhaustion effect. I don't know why, but it is gone and I am feeling great. I always take resveratrol daily, and many other supplements as noted above. I am also considering the other NAD precursor which is starting to become available, nicotinamide mononucleotide, but the price has got to come down significantly and some major advantage over NR demonstrated. Another possible effect from taking the 250 mg. NR dose is noteworthy: my fasting blood sugar is now running in the 60's and 70's regularly, but I do not feel bad. I have been doing a form of intermittent fasting for some time, but even when I have a regular meal, a few hours later my fasting glucose is back in the 60's & 70's. I test it daily. This may in fact serve as a long-term indicator of the continued efficacy of NR. I have never had fasting glucose levels this low, before taking 250 mg. of NR daily.

Its a great product! The 1st day you take it you notice you have more energy. However, the nature of our bodies is to get used to things, so after a few days you’ll not notice what you did at first. But, it is still working hard for you! And in a couple of weeks you will notice that you are thinking clearer, your thinking is more focused, and you have a better attitude towards things. A better attitude because the mind is now ‘more together’ and therefore more efficient! I like this for me. This supplement is not about feeling super energetic all the time, feeling like a superhero. Instead, its about providing you with results that when combined with a healthy lifestyle can help you get closer to reaching your highest potential. I recommend this product. Thank you HPN!

This is my main supplement for energy and mental clarity. I take this every day and I can feel a dramatic difference when I don’t take it. I have used many other NAD supplements and this is by far my favorite. Just solid energy and mental clarity. I trust this brand to other supplements as well.

EXCELLENT PRODUCT! packaged in GROSSLY EXCESSIVE PLASTIC — bottle is, at most, 1/4 full.

excelente

I'm 40 and in general good health. I already get lots of vitamins and minerals in my diet. I tried this for 30 days. I know they say it can take a couple weeks before you feel anything. Honestly, I'm not sure if I did. I felt *slightly* more energy and *slightly* clearer mental focus... but so slight, I'm not sure if it's just psychosomatic/placebo effect -or- I was just getting better sleep at the time anyway. Either way, it wasn't a significant contrast for me. Maybe I'm too young to reap its main benefits, or I'm already getting enough other healthy nutrition that my body doesn't need this. I want to believe this works and delivers on all its health promises. Honestly, I just wasn't feeling enough of a difference to continue purchasing it after I finished the first bottle. Of course, your mileage may vary. :)

I am a 62 years old gal and as a result of my lifestyle, choices in food, shopping for only safe, nontoxic products and an educated use of very high quality nutritional products for decades, I take no prescription drugs and my health markers are perfect. During my early 30's I was in a head on car accident which resulting in severe Traumatic Head Injury and experienced amnesia. I healed on the outside, but the injury to my brain resulted in internal scarring and long term changes in the way I think. Now 30 some years later, despite that fact that I run 3 business, am active outdoors, own and ride horses and generally am a wild and crazy gal, I more and more suffered from brain cloud, headaches and forgetfulness. I have used herbals over the years and I am sure that helped, but I am always looking for new developments. I read about this product and what it does, made complete sense to me. Bought my first bottle here at Amazon last week, along with Pterostilbene, 50 Mg. Have been taking two capsules of Niagen and one of Pterostilbene, every morning for the last five days first thing when I wake up. Have not changed anything else. Within 24-48 hours the difference ws incredible! No foggy weirdness. Short term memory much improved. I am impressed and thrilled. Will run through this month, take the recommended couple of days off and do again. Am hoping this result lasts long term, as it really is amazing the difference.

I had read articles about the human anti-aging trials starting this year so I took a chance on this. I'm 49 and I don't know about feeling 20 again, but I definitely feel like I'm 35 again. I started lifting weights again this past year (former college wrestler and coach) and had consigned myself to being to old to lift like I did even in my mid thirties. So I cut back on my workout routines, instead of doing 16 sets per muscle group, I had to cut back to 8 - 12 sets per muscle group. I figured at this age (going on 50) doing anything was good. Within 1 week of taking the Niagen I somehow had the energy to pump out 16 sets. I don't come home tired from work and only work out on weekends or have to slam caffeine pills and energy boosters to get a workout in. I feel good every day. I did my research and from what I gather this product works better for older people, the young body builders didn't report much of anything. But from my understanding this product helps protect the brain in contact sports, so I don't want to turn off everyone young. I have 3 sons that play football and if this product was cheaper I would put them on it.