---
product_id: 21658792
title: "API STRESS ZYME Bacterial cleaner, Freshwater and Saltwater Aquarium Water Cleaning Solution, 4 oz"
brand: "api"
price: "405896₫"
currency: VND
in_stock: true
reviews_count: 8
category: "Api"
url: https://www.desertcart.vn/products/21658792-api-stress-zyme-bacterial-cleaner-freshwater-and-saltwater-aquarium-water
store_origin: VN
region: Vietnam
---

# Safe for fresh & saltwater 300M+ live bacteria per tsp Reduces sludge & organic waste API STRESS ZYME Bacterial cleaner, Freshwater and Saltwater Aquarium Water Cleaning Solution, 4 oz

**Brand:** api
**Price:** 405896₫
**Availability:** ✅ In Stock

## Summary

> 🧪 Transform your tank into a self-cleaning aquatic paradise!

## Quick Answers

- **What is this?** API STRESS ZYME Bacterial cleaner, Freshwater and Saltwater Aquarium Water Cleaning Solution, 4 oz by api
- **How much does it cost?** 405896₫ with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vn](https://www.desertcart.vn/products/21658792-api-stress-zyme-bacterial-cleaner-freshwater-and-saltwater-aquarium-water)

## Best For

- api enthusiasts

## Why This Product

- Trusted api brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted Legacy:** Backed by 50+ years of API innovation, join thousands of aquarists who swear by Stress Zyme.
- • **Effortless Maintenance:** Consumes sludge and organic debris, keeping gravel and decorations pristine with zero scrubbing.
- • **Weekly Wellness Ritual:** Simple weekly dosing maintains a balanced, healthy environment your fish will thrive in.
- • **Universal Aquarium Care:** Formulated for both freshwater and saltwater tanks, perfect for any aquatic setup.
- • **Powerful Bioload Booster:** Over 300 million live bacteria per teaspoon turbocharge your aquarium’s natural cleaning cycle.

## Overview

API STRESS ZYME is a 4 oz liquid bacterial cleaner designed for freshwater and saltwater aquariums. It contains over 300 million live bacteria per teaspoon that naturally consume sludge, fish waste, and organic debris, reducing maintenance and promoting a healthy biological filter. Safe for all aquarium types, it supports a balanced ecosystem and has a proven track record with over 12,000 positive reviews and 50 years of trusted API research.

## Description

Reduce aquarium maintenance by creating a naturally balanced aquarium with API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution. Fish waste, sludge, uneaten food and other organic compounds can cause harmful water conditions including ammonia and nitrite poisoning and breathing difficulty. They can also be difficult and time-consuming to remove especially from rock, coral and gravel. API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution contains over 300 million live bacteria per teaspoonful to consume sludge and organic debris, keeping gravel and glass clean naturally and boosting the natural aquarium cycle, reducing aquarium maintenance over time. Use it weekly in freshwater and saltwater aquariums to maintain a strong biological filter and a healthy, clean aquarium. With API Aquarium products, it’s easy to keep a beautiful saltwater, freshwater or reef aquarium. For over 50 years, API has been creating innovative, research-driven solutions that make it easier to care for your fish and aquarium. API Aquarium Treatment Supplies are designed to work in conjunction with each other to provide best results to control algae, promote healthy bacterial growth and help control and cure fish diseases and conditions such as ich and fin rot. They work to provide a safe, hospitable environment for fish such as tropical community fish, cichlids, goldfish and more. With API, you can spend more time admiring your fish, and less time scrubbing your tank. Make sure to use all products as directed in order to ensure the best results.

Review: Good 👍 - Cleans good fish tank.
Review: Amazing product. Really works. - I use this weekly, RELIGIOUSLY. I do not miss a dose. This is my tank today, having not touched the filter in 18 months. (Fluval FX6 filled with only biohome filter media and polishing sponges.) I’ve only changed out the live plants when needed (pothos houseplant clippings) and used the magnetic algae glass scraper when needed. It’s a 75 gallon tank. I8 MONTHS!!! I highly recommend this product. Zero odor, zero nastiness.

## Features

- Contains one (1) API STRESS ZYME Freshwater and Saltwater Aquarium Water Cleaning Solution 4-Ounce Bottle
- Keeps freshwater and saltwater aquariums clean and reduces maintenance
- Consumes sludge to help keep gravel and decorations clean
- Adds beneficial bacteria for a healthy aquarium
- Use weekly to maintain a clean, healthy aquarium

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Brand | API |
| Customer Reviews | 4.7 out of 5 stars 12,002 Reviews |
| Item Form | Liquid |
| Item Weight | 136.08 Grams |
| Liquid Volume | 4 Fluid Ounces |
| Manufacturer | Mars Fishcare |
| UPC | 317163040560 |

## Product Details

- **Brand:** API
- **Liquid Volume:** 4 Fluid Ounces
- **Item Weight:** 136.08 Grams
- **Item Form:** Liquid
- **Manufacturer:** Mars Fishcare

## Images

![API STRESS ZYME Bacterial cleaner, Freshwater and Saltwater Aquarium Water Cleaning Solution, 4 oz - Image 1](https://m.media-amazon.com/images/I/71tav3eZUbL.jpg)

## Available Options

This product comes in different **Color, Size** options.

## Questions & Answers

**Q: Can I mix this with API Quick Start and API Stress Coat+ in a gallon every time I do water changes weekly? Or just pour it directly in my 5.5 tank?**
A: In short, you don't need the Stress Zyme if you already are using the Quick Start.  Here's a longer answer:The API Stress Coat is primarily a de-chlorinator and has aloe added to help maintain a healthy slime coat on the fish so this should always be added to the water and mixed before adding to the tank.  The API Quick Start is meant to jump start the biological cycling of a tank and is only needed for new tanks or potentially semi established tanks that have a spike in ammonia and nitrite levels which could be caused by adding more fish.  You can stop using this once your water chemistry has stabilized.  API Stress Zyme is very similar in function to the Quick Start and is generally chosen to improve water clarity or stabilize chemistry in more established tanks.    You don't need to use both simultaneously and would probably never see the difference compared to using just one.  On another note, I always add my bacteria after there is no chance there is any chlorine so they have a better chance of proliferating.  I would add either the Quick Start or the Stress Zyme the day after a water change, directly into the tank.

**Q: can i mix stress coat, stress zyme and tap water conditioner? if so what amount of each should i mix? doing this harm my fishes?**
A: Stress Coat and water conditioner is the same. ( stress Coat is water conditioner ). if you use both at the same time that you double it up. Maybe it is nothing will happening . But, it is not necessary to do that.

**Q: How long this product can be stored before it expires?  Also, would its effectiveness reduce during long time storage?**
A: As for length of time you can store, I use it weekly and it lasts for about four months or so. Does not seem to lose effectiveness in that time.

**Q: What is the expiration date on this Stress Zyme?  It seems very inexpensive.**
A: There is an expiration date on the bottle, however, these are live bacteria and once the bottle is open the shelf life is cut in half. Same as Seachems Pristine. Buy the size bottle for your tank. There is 250ml and 500 or 750ml, depending on the brand. My personal and professional advice is buy the smaller one 1st and see how much you go through, follow the instructions completely. They work well, keeps the glass cleaner longer. Also very important, make sure the aeriation is adequate and they say to change the filters 1st. If you have the $$ go for it. Best and least expensive and just as sufficient, is to change them half way before you normally change out your filters. API Stress zyme seems to keep its life span quite a while after opening. But trust me, you'll use it up way before it expires. Compared to the other similar products, this one seems to leave more of a brownish pile on the corners or underneath Ornaments, whis in turn will have to be vacuumed, netted or a baster for cooking depending on the size of your tank. 👍

## Customer Reviews

### ⭐⭐⭐⭐⭐ Good 👍
*by A***S on November 8, 2025*

Cleans good fish tank.

### ⭐⭐⭐⭐⭐ Amazing product. Really works.
*by A***6 on July 13, 2025*

I use this weekly, RELIGIOUSLY. I do not miss a dose. This is my tank today, having not touched the filter in 18 months. (Fluval FX6 filled with only biohome filter media and polishing sponges.) I’ve only changed out the live plants when needed (pothos houseplant clippings) and used the magnetic algae glass scraper when needed. It’s a 75 gallon tank. I8 MONTHS!!! I highly recommend this product. Zero odor, zero nastiness.

### ⭐⭐⭐⭐⭐ Great product and reliably works!
*by V***G on September 25, 2019*

Have used Stress Zyme for many, many years now in my tanks. It really does work. Some know-it-alls, claiming with their PHd's, ect. on fish forums, that this is bogus, that there is no live culture bacteria and can't work, that living bacteria cannot be kept alive in a bottle of liquid. Hogwash. Their medicine they take, such as liquid penicillin... is exactly that. Live bacteria in liquid form. In a bottle. Also that penicillin, the fact that it works, proves THIS bacteria also CAN and does work. The over edumacated people need to get educated on their facts and get them straight. Good bacteria culture NEEDS adding to your tanks to make them more like a good natural made spring fed lake or pond system has, good bacteria that 'mother nature' naturally adds. I have an irridescent shark in my tank, have had him/her since 1997. He/she is still healthy, never had any illness that needed treating. Even when I had other fish in the tank with it, this Stress Zyme cultures kept down the smell that a normal tank normally has. I can open the lid and sniff and virtually smell nothing. If I run out, and not use any for a while, the smell comes back, builds up. Start adding Stress Zyme again and the smell goes away. Fish are more alert and calmer with this added. Irridescents are very skittish and splashy fish. If they are calm, and if there is no smell to your tank when using this, then that means this stuff is working. 2 thumbs up.

## Frequently Bought Together

- API STRESS ZYME Bacterial cleaner, Freshwater and Saltwater Aquarium Water Cleaning Solution, 4 oz
- API STRESS COAT Aquarium Water Conditioner 4-Ounce Bottle (85B)
- API TAP WATER CONDITIONER Aquarium Water Conditioner 16-Ounce Bottle

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*Product available on Desertcart Vietnam*
*Store origin: VN*
*Last updated: 2026-02-11*