--- product_id: 15014844 title: "ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in the USA. 90 Tablets. Easy on the Gut. Not affected by Coffee, Calcium, or PPI's." brand: "proferrin" price: "3341631₫" currency: VND in_stock: true reviews_count: 8 category: "Proferrin" url: https://www.desertcart.vn/products/15014844-es-10-5mg-of-high-absorbing-heme-iron-polypeptide-made store_origin: VN region: Vietnam --- # Unaffected by coffee, calcium, PPIs 10.5mg high-absorption heme iron Made in USA, premium quality ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in the USA. 90 Tablets. Easy on the Gut. Not affected by Coffee, Calcium, or PPI's. **Brand:** proferrin **Price:** 3341631₫ **Availability:** ✅ In Stock ## Summary > 💪 Power your day with Proferrin—iron that works as hard as you do! ## Quick Answers - **What is this?** ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in the USA. 90 Tablets. Easy on the Gut. Not affected by Coffee, Calcium, or PPI's. by proferrin - **How much does it cost?** 3341631₫ with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.vn](https://www.desertcart.vn/products/15014844-es-10-5mg-of-high-absorbing-heme-iron-polypeptide-made) ## Best For - proferrin enthusiasts ## Why This Product - Trusted proferrin brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Made in the USA:** Crafted with trusted quality standards by Colorado Biolabs, ensuring purity and potency. - • **Long-Lasting Supply:** 90 tablets per bottle, supporting your iron needs for up to a month with flexible dosing. - • **Gut-Friendly Formula:** Gentle on your digestive system—no bloating or discomfort, even with daily use. - • **Effortless Iron Boost:** 10.5mg of highly bioavailable heme iron polypeptide for superior absorption and energy restoration. - • **Unstoppable Absorption:** Iron uptake remains effective regardless of coffee, calcium, or PPI intake—no more timing hassles. ## Overview Proferrin ES delivers 10.5mg of highly absorbable heme iron polypeptide per tablet, designed for maximum iron uptake without gastrointestinal side effects. Made in the USA, this gluten-free supplement maintains efficacy even when taken with coffee, calcium, or proton pump inhibitors, offering a convenient and reliable solution for iron support. Each bottle contains 90 easy-to-take tablets, perfect for busy professionals seeking sustained energy and wellness. ## Description Buy Proferrin ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in the USA. 90 Tablets. Easy on the Gut. Not affected by Coffee, Calcium, or PPI's. on desertcart.com ✓ FREE SHIPPING on qualified orders Review: Increases ferritin. Zero side effects. Take 3 daily, cut pills to facilitate disintegration. - 23 days of proferrin, and my ferritin has gone from 18 to 32. No side effects to speak of, except that I can run with energy again. It is such a gift to feel my strength again, like youth. I'm continuing with this. I was taking iron bis-glycinate, but while effective when taken on an empty stomach, I felt like I had swallowed a balloon. When I took iron bis-glycinate with meals (away from calcium), it was not effective after 4 months of use. I take proferrin with meat stock first thing in the morning; apparently it absorbs better in the presence of amino acids: "free amino acids as cysteine, lysine and histidine enhanced heme and ionic Fe absorption in experimental models". Also iron absorption is apparently not sensitive to calcium in doses of less than 800 mg at a time. "Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 milligrams". Where other forms of iron are inhibited by phytates and polyphenols, heme iron is not. Lastly, I understand (hopefully correctly) that heme iron may cause less oxidative stress than other forms. I hope that as a result, it lowers the risk of Alzheimer's disease associated with iron supplementation. Update: I was taking 1 pill per day at the time of this review. Since then my ferritin levels dropped to 20, so I began taking 2 per day. Fortunately I did this without any gastrointestinal upset, but unfortunately, 2/day only brought my ferritin up to 21 (I got this blood test result back today). Iron repletion is obviously extraordinarily complex. I'm baffled by it. Update July 2018: My ferritin dropped to 20, then to 17, 13, and finally to 10 while taking approximately 7 proferrin per week. During that time I tried alternating schedules, taking it with broth, lactoferrin, pepsin. Nothing worked. Once my ferritin had dropped to 10, I decided to take 30 mg per day, which is apparently the max you can take without causing expression of Hepcidin (prevents the uptake of iron). Also, I had been inspecting my stool (I know, gross...) and found pockets of dry black powder from undissolved proferrin pills. These pills look like black charcoal on the inside, which is probably why the coat is colored (green). Obviously absorption won't happen if they haven't dissolved. I started taking 3 pills (30 mgs) each morning, all at once, on an empty stomach, away from calcium. Most importantly, I cut each pill in half before taking, which seemed to help disintegration because I found no more black powder in stools. As a result, my ferritin climbed back up to 17 after 1 month of this routine. I'll continue checking ferritin levels each month until it has reached a steady state. Hopefully no more downturns. Update November 2018: My monthly ferritin levels have continued to rise on the schedule of three pills per day, cut, on an empty stomach, and away from calcium. Here are my ferritin results (ng/ml): August (16), September (21), October (25), and November (40). Awesome. Feeling so much better. Review: Proferrin - This was recommended by my Doctor, very gentle on the stomach! Works well! ## Features - Oral Heme Iron - 10.5 mg of Iron as Heme Iron Polypeptide - Naturally occurring iron source - Recommended Use: Take one tablet up to three times daily, with or without food - Made in the USA by Colorado Biolabs, Inc - During the summer months products may arrive warm but desertcart stores and ships products in accordance with manufacturers' recommendations, when provided. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00MJPVZC6 | | Allergen Information | Gluten Free | | Best Sellers Rank | #11,057 in Health & Household ( See Top 100 in Health & Household ) #55 in Iron Mineral Supplements #1,118 in Sales & Deals | | Brand | Proferrin | | Brand Name | Proferrin | | Customer Reviews | 4.5 out of 5 stars 1,250 Reviews | | Diet Type | Gluten Free | | Flavor | Unflavored | | Global Trade Identification Number | 00645130201011 | | Item Form | Tablets | | Item Weight | 0.23 Pounds | | Manufacturer | Proferrin ES | | Manufacturer Part Number | GHSTM | | Material Type Free | Gluten Free | | Model Number | GHSTM | | Number of Items | 1 | | Primary Supplement Type | Iron | | Product Benefits | Iron Support | | UPC | 767644013727 645130201011 | | Unit Count | 90 Count | ## Product Details - **Brand:** Proferrin - **Flavor:** Unflavored - **Item Form:** Tablets - **Primary Supplement Type:** Iron - **Unit Count:** 90 Count ## Images ![ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in the USA. 90 Tablets. Easy on the Gut. Not affected by Coffee, Calcium, or PPI's. - Image 1](https://m.media-amazon.com/images/I/515MZxzhXzL.jpg) ## Available Options This product comes in different **Size, Flavor** options. ## Questions & Answers **Q: Why are there such bad ingredients?? Colors?!!** A: Hi There! Thank you for the question! Currently, we also make Proferrin Clear which is free from all colors/dyes and is also available on Amazon. Proferrin Clear and Proferrin ES have the exact same amount of Heme Iron. Best, Team Proferrin **Q: Is it vegetarian?** A: No, it is not vegetarian. It is derived from the hemoglobin of cows. It has been amazing for improving my hemoglobin. **Q: Can you please tell me what the expiration date is on this bottle?** A: Its on the side of the bottle **Q: Anyone know why this product contains so many unhealthy inactive ingredients (artificial colors, talc, titanium dioxide, polyvinyl...)?** A: Hi there! Thank you for the question! We do have a product called Proferrin Clear that comes in a gel capsule. The gel capsule does not have the coating on it that the ES tablet does, so it has a smaller ingredient list with only 4 ingredients. Both the Proferrin Clear and the Proferrin ES have the same amount of Heme Iron. Thanks, Team Proferrin ## Customer Reviews ### ⭐⭐⭐⭐⭐ Increases ferritin. Zero side effects. Take 3 daily, cut pills to facilitate disintegration. *by L***I on September 21, 2017* 23 days of proferrin, and my ferritin has gone from 18 to 32. No side effects to speak of, except that I can run with energy again. It is such a gift to feel my strength again, like youth. I'm continuing with this. I was taking iron bis-glycinate, but while effective when taken on an empty stomach, I felt like I had swallowed a balloon. When I took iron bis-glycinate with meals (away from calcium), it was not effective after 4 months of use. I take proferrin with meat stock first thing in the morning; apparently it absorbs better in the presence of amino acids: "free amino acids as cysteine, lysine and histidine enhanced heme and ionic Fe absorption in experimental models". Also iron absorption is apparently not sensitive to calcium in doses of less than 800 mg at a time. "Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 milligrams". Where other forms of iron are inhibited by phytates and polyphenols, heme iron is not. Lastly, I understand (hopefully correctly) that heme iron may cause less oxidative stress than other forms. I hope that as a result, it lowers the risk of Alzheimer's disease associated with iron supplementation. Update: I was taking 1 pill per day at the time of this review. Since then my ferritin levels dropped to 20, so I began taking 2 per day. Fortunately I did this without any gastrointestinal upset, but unfortunately, 2/day only brought my ferritin up to 21 (I got this blood test result back today). Iron repletion is obviously extraordinarily complex. I'm baffled by it. Update July 2018: My ferritin dropped to 20, then to 17, 13, and finally to 10 while taking approximately 7 proferrin per week. During that time I tried alternating schedules, taking it with broth, lactoferrin, pepsin. Nothing worked. Once my ferritin had dropped to 10, I decided to take 30 mg per day, which is apparently the max you can take without causing expression of Hepcidin (prevents the uptake of iron). Also, I had been inspecting my stool (I know, gross...) and found pockets of dry black powder from undissolved proferrin pills. These pills look like black charcoal on the inside, which is probably why the coat is colored (green). Obviously absorption won't happen if they haven't dissolved. I started taking 3 pills (30 mgs) each morning, all at once, on an empty stomach, away from calcium. Most importantly, I cut each pill in half before taking, which seemed to help disintegration because I found no more black powder in stools. As a result, my ferritin climbed back up to 17 after 1 month of this routine. I'll continue checking ferritin levels each month until it has reached a steady state. Hopefully no more downturns. Update November 2018: My monthly ferritin levels have continued to rise on the schedule of three pills per day, cut, on an empty stomach, and away from calcium. Here are my ferritin results (ng/ml): August (16), September (21), October (25), and November (40). Awesome. Feeling so much better. ### ⭐⭐⭐⭐⭐ Proferrin *by R***P on March 20, 2026* This was recommended by my Doctor, very gentle on the stomach! Works well! ### ⭐⭐⭐⭐⭐ EExtremely effective at raising blood iron levels in the red blood cells. *by N***N on April 3, 2026* Really does work. My girlfriend had iron below the minimum allowed - so red flagged as dangerous. They wanted to do an intravenous iron but she didn't want to go to the hospital. So we tried having her take these 3 times a day for three weeks (and extra B-12) and her iron levels are no longer flagged as dangerously low and are acceptable low (through she does needs to get higher in my opinion. So, will continue with that dosing for a few more months and see the results. ## Frequently Bought Together - Proferrin ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in The USA. 90 Tablets. Easy on The Gut. Not affected by Coffee, Calcium, or PPI's. - Bio-Tech - K1-1000 (Vitamin K-1) 100 Capsules - MSNOR Bio-Tech Pharmacal A-25 Vitamin A 25,000 IU - 100 Capsules --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.vn/products/15014844-es-10-5mg-of-high-absorbing-heme-iron-polypeptide-made](https://www.desertcart.vn/products/15014844-es-10-5mg-of-high-absorbing-heme-iron-polypeptide-made) --- *Product available on Desertcart Vietnam* *Store origin: VN* *Last updated: 2026-04-24*